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    Pilar Cyst: eMedicine Dermatology
  • Pilar cysts are the second most frequent type of ... In 2% of pilar cysts, single or multiple foci of proliferating cells lead to ...
  • http://emedicine.medscape.com/article/1058907-overview
Questions/Answers
Can pilar cysts have anysymptoms/effects?
I have a pilar cyst on the back of my head, on the lower right side. It seems to be pretty sizeable, maybe about .5" (possibly less?) in width. Now my question is, can this have any symptoms or negative effects, as far as motor control/brain function/etc? I've always had headaches and they seem to come from the back of my head. It also really feels like the cyst is pushing against sometime and puts pressure on it. Not sure if that's just me feeling it, but is that possible?
Here's a website that will give you the information you need. http://www.patient.co.uk/showd oc/23068818/
pilar cysts?
I was wondering if anyone has every had pilar cysts. I get them on my scalp, that aren't noticable because i have longer thick hair but they're annoying and they can be tender and hurt. I got a few of them removed but they still grow. They're just tiny bumps and i obviously can't get all of them removed all the time that's a lot of time and money and surgery! Does anyone have them and put up with theM?
There is more at the link. Pilar cysts are common, occurring in 5-10% of population. They are the second most common keratinizing cyst on the scalp. Their benign and malignant transformation is extremely rare. Inheritance may occur in an autosomal dominant pattern. Pilar or trichilemmal cysts contain keratin and its breakdown products, lined by a wall resembling the external (outer) hair root sheath. Most pilar cysts occur on the scalp. In 2% of pilar cysts, single or multiple foci of proliferating cells that can lead to rare cases of proliferating pilar tumors, more commonly called proliferating trichilemmal cysts, have been observed. They were originally considered malignant; however, Wilson Jones suggested that they are pseudocarcinomatous. Proliferating trichilemmal cysts are rapidly growing tumors that often occur in trichilemmal cysts, but they can occur de novo without a preexisting lesion. The tumors may become large and ulcerated. Although considered biologically benign, the cysts may be locally aggressive. In rare cases, malignant transformation has occurred as demonstrated by distant metastasis. No reliable clinical criteria exist to distinguish a malignant tumor from a benign proliferating pilar tumor. The entire lesion must be histologically evaluated to assess the possibility of malignancy. Pathophysiology: Trichilemmal cysts are derived from the outer root sheath of the hair follicle. Their origin is unknown, but it has been suggested that they are produced by budding from the external root sheath as a genetically determined structural aberration. They arise preferentially in areas of dense hair follicle concentrations; therefore, 90% of cases occur on the scalp. They are solitary in 30% of cases and multiple in 70% of cases. Histologically, areas with signs of proliferation can be found in some cysts. In rare cases, this leads to formation of a tumor, known as a proliferating trichilemmal cyst. The tumor is clinically benign, although it may display nuclear atypia, dyskeratotic cells, and mitotic figures. These features can be misleading, and a diagnosis of squamous cell carcinoma may be mistakenly rendered. Frequency: In the US: Pilar cysts are common, occurring in 5-10% of the population. Of patients with these cysts, 70% have several lesions and 10% have more than 10 lesions. Mortality/Morbidity: Pilar cysts are considered biologically benign, but they may be locally aggressive. Malignant transformation has occurred in rare cases, as demonstrated by distant metastasis.
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