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How do indirectly actingparasympathomimetic drugswork?
I undestand how the anticholinesterase prevents Ach breakdown is the synaptic cleft, thus the Ach accumalates. Does this then mean the PSNS secretes more Ach?
From Encyclopedia.com: parasympathomimetic adj. n. (Of, relating to, or having an effect similar to) a drug such as carbachol, methacholine, or muscarine that mimics or increases the activity of acetylcholine, the major neurotransmitter of the parasympathetic nervous system. Most articles quote mimics, this one also says increases so I would assume the PSNS does secrete more Ach.
how safe is insect killer ,tohumans ,on garden vegetables?
i grow herbs and veg.in pots ,the stuff i got to control things from eating them kills a variety of pests .it says not to pick edible plants for 2 weeks after treatment. given that the remaining stuff is still in the ground ,wouldn't the plants absorb it? or does it leach away? active constituent:40g/Kg chlorpyrifos (an anticholinesterase compound) is there a natural way of keeping pests at bay?
My ancestors including my grandparents on both sides were market gardeners who used organic gardening methods. However their neighbours used pesticides and this stuff blows in the air. When I was a kid and used to help pick carrots, radishes, parsnips and beetroot and wash them it was such fun because the washing shed ( I called it the carrot shed) smelt like fresh, crunchy sweet yummy carrots. The garden and surrounding land and lake was sold when I was about twenty and my dad would buy carrots from a market gardeners stall just a few k's from our place. The carrots were slightly smaller (yet still bigger and more colourful than those sold in the supermarket chain stores) however my dad said that the funny smell I detected on them was Dildren, a pesticide. I have moved back to this area with the lake (with my family) as it is very pretty with it's surrounding natural bush. A church is now on my grandparents old house site. Now some of my contacts may remember that I have Multiple Sclerosis. Several of my cousins daughters (from my fathers side) have similar neurological disorders as well. My father had Non Hodgkin's Lymphoma which morphed into Chronic Lymphatic Leukemia. A cousin on my fathers side had Non Hodgkin's Leukemia in her teens and recovered; hopefully she wont have a relapse. I have hints that I may be getting Non Hodgkins Lymphoma as my blood cells and vessels are doing funny things. But I try to eat healthy fruits and vegetables ... yes well I try... that stuff stays in the soil for many years I am told. I have spoken to a medical researcher (who owns his own laboratory here in Murdoch, Western Australia) whose interests lie in the study of blood and bone cancers. He told me that such cancers are most prevalent in the country farming areas as well as market garden areas which tend to be in the outer suburbs of cities and towns. This is in keeping with the use of pesticides. He also said that Parkinson's Disease is a common illness among farmers as well as other neurological conditions. I have heard that Marigolds keep some bugs away from tomatoes. And garlic planted around roses and other plants keep aphids and other nasties away. It is called companion gardening. I think I'll go eat some Marigolds and Garlic.
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